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Integrator is recruited to promoter‐proximally paused RNA Pol II to generate Caenorhabditis elegans piRNA precursors

Piwi‐interacting RNAs (piRNAs) play key roles in germline development and genome defence in metazoans. In C. elegans, piRNAs are transcribed from > 15,000 discrete genomic loci by RNA polymerase II (Pol II), resulting in 28 nt short‐capped piRNA precursors. Here, we investigate transcription term...

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Detalles Bibliográficos
Autores principales:	Beltran, Toni, Pahita, Elena, Ghosh, Subhanita, Lenhard, Boris, Sarkies, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917550/ https://www.ncbi.nlm.nih.gov/pubmed/33340372 http://dx.doi.org/10.15252/embj.2020105564

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