A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis

Primary hyperparathyroidism (PHPT) typically occurs in persons above 45 years, with a female predominance. PHPT induces a state of hypercalcemia, but acute pancreatitis is a rare sequelae of this hypercalcemia. We report a case of a 31-year-old man with no known medical history who presented in diab...

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Autores principales: Mills, Krystal, Aniekwena, Judith, Cochran, Tiffany, Nsofor, Echezona, Bakinde, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917841/
https://www.ncbi.nlm.nih.gov/pubmed/33631992
http://dx.doi.org/10.1177/2324709621998477
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author Mills, Krystal
Aniekwena, Judith
Cochran, Tiffany
Nsofor, Echezona
Bakinde, Nicolas
author_facet Mills, Krystal
Aniekwena, Judith
Cochran, Tiffany
Nsofor, Echezona
Bakinde, Nicolas
author_sort Mills, Krystal
collection PubMed
description Primary hyperparathyroidism (PHPT) typically occurs in persons above 45 years, with a female predominance. PHPT induces a state of hypercalcemia, but acute pancreatitis is a rare sequelae of this hypercalcemia. We report a case of a 31-year-old man with no known medical history who presented in diabetic ketoacidosis with electrolyte abnormalities. His clinical course progressed to multi-organ dysfunction despite correction of metabolic derangements. Further workup led to the discovery of the uncommon triad by which previously undiagnosed PHPT precipitated severe diabetic ketoacidosis.
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spelling pubmed-79178412021-03-11 A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis Mills, Krystal Aniekwena, Judith Cochran, Tiffany Nsofor, Echezona Bakinde, Nicolas J Investig Med High Impact Case Rep Case Report Primary hyperparathyroidism (PHPT) typically occurs in persons above 45 years, with a female predominance. PHPT induces a state of hypercalcemia, but acute pancreatitis is a rare sequelae of this hypercalcemia. We report a case of a 31-year-old man with no known medical history who presented in diabetic ketoacidosis with electrolyte abnormalities. His clinical course progressed to multi-organ dysfunction despite correction of metabolic derangements. Further workup led to the discovery of the uncommon triad by which previously undiagnosed PHPT precipitated severe diabetic ketoacidosis. SAGE Publications 2021-02-25 /pmc/articles/PMC7917841/ /pubmed/33631992 http://dx.doi.org/10.1177/2324709621998477 Text en © 2021 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Mills, Krystal
Aniekwena, Judith
Cochran, Tiffany
Nsofor, Echezona
Bakinde, Nicolas
A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis
title A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis
title_full A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis
title_fullStr A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis
title_full_unstemmed A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis
title_short A Rare Triad: Hypercalcemia-Induced Necrotizing Pancreatitis Presenting as Severe Diabetic Ketoacidosis
title_sort rare triad: hypercalcemia-induced necrotizing pancreatitis presenting as severe diabetic ketoacidosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917841/
https://www.ncbi.nlm.nih.gov/pubmed/33631992
http://dx.doi.org/10.1177/2324709621998477
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