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Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome

The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is an uncommon cause of cardiac hypertrophy, fibrosis, and dysfunction. It shares similar features to numerous other causes of left ventricular hypertrophy, and therefore, because of its rarity, ma...

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Autores principales: Reid, Anna B., Venetucci, Luigi, Schmitt, Matthias, Nucifora, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917926/
https://www.ncbi.nlm.nih.gov/pubmed/33673315
http://dx.doi.org/10.3390/diagnostics11020295
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author Reid, Anna B.
Venetucci, Luigi
Schmitt, Matthias
Nucifora, Gaetano
author_facet Reid, Anna B.
Venetucci, Luigi
Schmitt, Matthias
Nucifora, Gaetano
author_sort Reid, Anna B.
collection PubMed
description The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is an uncommon cause of cardiac hypertrophy, fibrosis, and dysfunction. It shares similar features to numerous other causes of left ventricular hypertrophy, and therefore, because of its rarity, may not be immediately considered as a diagnosis. Prompt recognition of clinical and cardiac imaging features may expedite diagnosis and management. We report the case of a 38-year-old man admitted with neurological symptoms and in whom the diagnostic workup led to the diagnosis of MELAS syndrome with cardiac involvement.
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spelling pubmed-79179262021-03-02 Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome Reid, Anna B. Venetucci, Luigi Schmitt, Matthias Nucifora, Gaetano Diagnostics (Basel) Interesting Images The mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is an uncommon cause of cardiac hypertrophy, fibrosis, and dysfunction. It shares similar features to numerous other causes of left ventricular hypertrophy, and therefore, because of its rarity, may not be immediately considered as a diagnosis. Prompt recognition of clinical and cardiac imaging features may expedite diagnosis and management. We report the case of a 38-year-old man admitted with neurological symptoms and in whom the diagnostic workup led to the diagnosis of MELAS syndrome with cardiac involvement. MDPI 2021-02-12 /pmc/articles/PMC7917926/ /pubmed/33673315 http://dx.doi.org/10.3390/diagnostics11020295 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Interesting Images
Reid, Anna B.
Venetucci, Luigi
Schmitt, Matthias
Nucifora, Gaetano
Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
title Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
title_full Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
title_fullStr Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
title_full_unstemmed Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
title_short Unraveling an Unusual Phenocopy of Hypertrophic Cardiomyopathy: MELAS Syndrome
title_sort unraveling an unusual phenocopy of hypertrophic cardiomyopathy: melas syndrome
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917926/
https://www.ncbi.nlm.nih.gov/pubmed/33673315
http://dx.doi.org/10.3390/diagnostics11020295
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