Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer

Germline mutations in predisposition genes account for only 20% of all familial colorectal cancers (CRC) and the remaining genetic burden may be due to rare high- to moderate-penetrance germline variants that are not explored. With the aim of identifying such potential cancer-predisposing variants,...

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Detalles Bibliográficos
Autores principales: Skopelitou, Diamanto, Miao, Beiping, Srivastava, Aayushi, Kumar, Abhishek, Kuswick, Magdalena, Dymerska, Dagmara, Paramasivam, Nagarajan, Schlesner, Matthias, Lubinski, Jan, Hemminki, Kari, Försti, Asta, Bandapalli, Obul Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917948/
https://www.ncbi.nlm.nih.gov/pubmed/33673279
http://dx.doi.org/10.3390/ijms22041837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917948/
https://www.ncbi.nlm.nih.gov/pubmed/33673279
http://dx.doi.org/10.3390/ijms22041837

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