Pharyngeal Pumping and Tissue-Specific Transgenic P-Glycoprotein Expression Influence Macrocyclic Lactone Susceptibility in Caenorhabditis elegans

Macrocyclic lactones (MLs) are widely used drugs to treat and prevent parasitic nematode infections. In many nematode species including a major pathogen of foals, Parascaris univalens, resistance against MLs is widespread, but the underlying resistance mechanisms and ML penetration routes into nemat...

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Detalles Bibliográficos
Autores principales: Gerhard, Alexander P., Krücken, Jürgen, Neveu, Cedric, Charvet, Claude L., Harmache, Abdallah, von Samson-Himmelstjerna, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917992/
https://www.ncbi.nlm.nih.gov/pubmed/33668460
http://dx.doi.org/10.3390/ph14020153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917992/
https://www.ncbi.nlm.nih.gov/pubmed/33668460
http://dx.doi.org/10.3390/ph14020153

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