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Pharyngeal Pumping and Tissue-Specific Transgenic P-Glycoprotein Expression Influence Macrocyclic Lactone Susceptibility in Caenorhabditis elegans
Macrocyclic lactones (MLs) are widely used drugs to treat and prevent parasitic nematode infections. In many nematode species including a major pathogen of foals, Parascaris univalens, resistance against MLs is widespread, but the underlying resistance mechanisms and ML penetration routes into nemat...
Autores principales: | Gerhard, Alexander P., Krücken, Jürgen, Neveu, Cedric, Charvet, Claude L., Harmache, Abdallah, von Samson-Himmelstjerna, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917992/ https://www.ncbi.nlm.nih.gov/pubmed/33668460 http://dx.doi.org/10.3390/ph14020153 |
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