Cross-Talk of Toll-Like Receptor 5 and Mu-Opioid Receptor Attenuates Chronic Constriction Injury-Induced Mechanical Hyperalgesia through a Protein Kinase C Alpha-Dependent Signaling

Recently, Toll-like receptors (TLRs), a family of pattern recognition receptors, are reported as potential modulators for neuropathic pain; however, the desired mechanism is still unexplained. Here, we operated on the sciatic nerve to establish a pre-clinical rodent model of chronic constriction inj...

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Detalles Bibliográficos
Autores principales: Chang, Ching, Liu, Hung-Kai, Yeh, Chao-Bin, Yang, Ming-Lin, Liao, Wen-Chieh, Liu, Chiung-Hui, Tseng, To-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918001/
https://www.ncbi.nlm.nih.gov/pubmed/33673008
http://dx.doi.org/10.3390/ijms22041891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918001/
https://www.ncbi.nlm.nih.gov/pubmed/33673008
http://dx.doi.org/10.3390/ijms22041891

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