Cargando…
Cross-Talk of Toll-Like Receptor 5 and Mu-Opioid Receptor Attenuates Chronic Constriction Injury-Induced Mechanical Hyperalgesia through a Protein Kinase C Alpha-Dependent Signaling
Recently, Toll-like receptors (TLRs), a family of pattern recognition receptors, are reported as potential modulators for neuropathic pain; however, the desired mechanism is still unexplained. Here, we operated on the sciatic nerve to establish a pre-clinical rodent model of chronic constriction inj...
Autores principales: | Chang, Ching, Liu, Hung-Kai, Yeh, Chao-Bin, Yang, Ming-Lin, Liao, Wen-Chieh, Liu, Chiung-Hui, Tseng, To-Jung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918001/ https://www.ncbi.nlm.nih.gov/pubmed/33673008 http://dx.doi.org/10.3390/ijms22041891 |
Ejemplares similares
-
Morphine-induced hyperalgesia involves mu opioid receptors and the metabolite morphine-3-glucuronide
por: Roeckel, Laurie-Anne, et al.
Publicado: (2017) -
Toll-like Receptor-Dependent Negative Effects of Opioids: A Battle between Analgesia and Hyperalgesia
por: Shah, Masaud, et al.
Publicado: (2017) -
Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia
por: Oladosu, Folabomi A., et al.
Publicado: (2015) -
Curcumin Attenuates Mechanical and Thermal Hyperalgesia in Chronic Constrictive Injury Model of Neuropathic Pain
por: Di, Yu Xiang, et al.
Publicado: (2014) -
Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D(2) Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
por: Vasudevan, Lakshmi, et al.
Publicado: (2019)