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Herbal Medicine for Pain Management: Efficacy and Drug Interactions

Complementary and alternative medicines such as herbal medicines are not currently part of the conventional medical system. As the popularity of and global market for herbal medicine grows among all age groups, with supporting scientific data and clinical trials, specific alternative treatments such...

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Autores principales: Jahromi, Behdad, Pirvulescu, Iulia, Candido, Kenneth D., Knezevic, Nebojsa Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918078/
https://www.ncbi.nlm.nih.gov/pubmed/33670393
http://dx.doi.org/10.3390/pharmaceutics13020251
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author Jahromi, Behdad
Pirvulescu, Iulia
Candido, Kenneth D.
Knezevic, Nebojsa Nick
author_facet Jahromi, Behdad
Pirvulescu, Iulia
Candido, Kenneth D.
Knezevic, Nebojsa Nick
author_sort Jahromi, Behdad
collection PubMed
description Complementary and alternative medicines such as herbal medicines are not currently part of the conventional medical system. As the popularity of and global market for herbal medicine grows among all age groups, with supporting scientific data and clinical trials, specific alternative treatments such as herbal medicine can be reclassified as a practice of conventional medicine. One of the most common conditions for which adults use herbal medicine is pain. However, herbal medicines carry safety concerns and may impact the efficacy of conventional therapies. Unfortunately, mechanisms of action are poorly understood, and their use is unregulated and often underreported to medical professionals. This review aims to compile common and available herbal medicines which can be used as an alternative to or in combination with conventional pain management approaches. Efficacy and safety are assessed through clinical studies on pain relief. Ensuing herb–drug interactions such as cytochrome modulation, additive and synergistic effects, and contraindications are discussed. While self-management has been recognized as part of the overall treatment strategy for patients suffering from chronic pain, it is important for practitioners to be able to also optimize and integrate herbal medicine and, if warranted, other complementary and alternative medicines into their care.
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spelling pubmed-79180782021-03-02 Herbal Medicine for Pain Management: Efficacy and Drug Interactions Jahromi, Behdad Pirvulescu, Iulia Candido, Kenneth D. Knezevic, Nebojsa Nick Pharmaceutics Review Complementary and alternative medicines such as herbal medicines are not currently part of the conventional medical system. As the popularity of and global market for herbal medicine grows among all age groups, with supporting scientific data and clinical trials, specific alternative treatments such as herbal medicine can be reclassified as a practice of conventional medicine. One of the most common conditions for which adults use herbal medicine is pain. However, herbal medicines carry safety concerns and may impact the efficacy of conventional therapies. Unfortunately, mechanisms of action are poorly understood, and their use is unregulated and often underreported to medical professionals. This review aims to compile common and available herbal medicines which can be used as an alternative to or in combination with conventional pain management approaches. Efficacy and safety are assessed through clinical studies on pain relief. Ensuing herb–drug interactions such as cytochrome modulation, additive and synergistic effects, and contraindications are discussed. While self-management has been recognized as part of the overall treatment strategy for patients suffering from chronic pain, it is important for practitioners to be able to also optimize and integrate herbal medicine and, if warranted, other complementary and alternative medicines into their care. MDPI 2021-02-11 /pmc/articles/PMC7918078/ /pubmed/33670393 http://dx.doi.org/10.3390/pharmaceutics13020251 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jahromi, Behdad
Pirvulescu, Iulia
Candido, Kenneth D.
Knezevic, Nebojsa Nick
Herbal Medicine for Pain Management: Efficacy and Drug Interactions
title Herbal Medicine for Pain Management: Efficacy and Drug Interactions
title_full Herbal Medicine for Pain Management: Efficacy and Drug Interactions
title_fullStr Herbal Medicine for Pain Management: Efficacy and Drug Interactions
title_full_unstemmed Herbal Medicine for Pain Management: Efficacy and Drug Interactions
title_short Herbal Medicine for Pain Management: Efficacy and Drug Interactions
title_sort herbal medicine for pain management: efficacy and drug interactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918078/
https://www.ncbi.nlm.nih.gov/pubmed/33670393
http://dx.doi.org/10.3390/pharmaceutics13020251
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