Takotsubo stress cardiomyopathy following explantation of sEEG electrodes

OBJECTIVE: Takotsubo stress cardiomyopathy is characterized by dysfunction of the left ventricle of the heart including apical ballooning and focal wall‐motion abnormalities. Although reported in association with seizures and intracerebral hemorrhage, there are no studies reporting its occurrence in patients having stereoelectroencephalography (sEEG). METHODS: A 38‐year‐old lady with no prior history of cardiac disease experienced sudden onset chest pain and acute left ventricular failure 4 hours following explantation of stereoelectroencephalogram electrodes. RESULTS: A small parenchymal hematoma related to the right posterior temporal electrode had been noted postelectrode insertion but was asymptomatic. Focal‐onset seizures from nondominant mesial temporal structures were recorded during sEEG. Following the presentation with LVF, new‐onset anterolateral T‐wave inversion with reciprocal changes in leads II, III, and aVF was noted on electrocardiogram (ECG) and the chest X‐ray findings were consistent with pulmonary edema. Echocardiography demonstrated hypokinesis of the cardiac apex and septum consistent with Takotsubo stress cardiomyopathy. SIGNIFICANCE: Awareness of the possible complication of Takotsubo stress cardiomyopathy is required in an epilepsy surgery program.