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Bi-Functional Radiotheranostics of (188)Re-Liposome-Fcy-hEGF for Radio- and Chemo-Therapy of EGFR-Overexpressing Cancer Cells

Epidermal growth factor receptor (EGFR) specific therapeutics is of great importance in cancer treatment. Fcy-hEGF fusion protein, composed of yeast cytosine deaminase (Fcy) and human EGF (hEGF), is capable of binding to EGFR and enzymatically convert 5-fluorocytosine (5-FC) to 1000-fold toxic 5-flu...

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Detalles Bibliográficos
Autores principales:	Huang, Yi-Shu, Hsu, Wei-Chuan, Lin, Chien-Hong, Lo, Sheng-Nan, Cheng, Chu-Nian, Lin, Ming-Syuan, Lee, Te-Wei, Chang, Chih-Hsien, Lan, Keng-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918434/ https://www.ncbi.nlm.nih.gov/pubmed/33672989 http://dx.doi.org/10.3390/ijms22041902

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