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Proposed Mechanism for the Antitrypanosomal Activity of Quercetin and Myricetin Isolated from Hypericum afrum Lam.: Phytochemistry, In Vitro Testing and Modeling Studies

The in vitro activity of L. donovani (promastigotes, axenic amastigotes and intracellular amastigotes in THP1 cells) and T. brucei, from the fractions obtained from the hydroalcoholic extract of the aerial part of Hypericum afrum and the isolated compounds, has been evaluated. The chloroform, ethyl...

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Detalles Bibliográficos
Autores principales: Larit, Farida, Elokely, Khaled M., Nael, Manal A., Benyahia, Samira, León, Francisco, Cutler, Stephen J., Ghoneim, Mohammed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918497/
https://www.ncbi.nlm.nih.gov/pubmed/33672916
http://dx.doi.org/10.3390/molecules26041009