SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus

Development of sensitive techniques for rapid detection of viruses is on a high demand. Surface-enhanced Raman spectroscopy (SERS) is an appropriate tool for new techniques due to its high sensitivity. DNA aptamers are short structured oligonucleotides that can provide specificity for SERS biosensor...

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Autores principales: Gribanyov, Dmitry, Zhdanov, Gleb, Olenin, Andrei, Lisichkin, Georgii, Gambaryan, Alexandra, Kukushkin, Vladimir, Zavyalova, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918581/
https://www.ncbi.nlm.nih.gov/pubmed/33673314
http://dx.doi.org/10.3390/ijms22041842
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author Gribanyov, Dmitry
Zhdanov, Gleb
Olenin, Andrei
Lisichkin, Georgii
Gambaryan, Alexandra
Kukushkin, Vladimir
Zavyalova, Elena
author_facet Gribanyov, Dmitry
Zhdanov, Gleb
Olenin, Andrei
Lisichkin, Georgii
Gambaryan, Alexandra
Kukushkin, Vladimir
Zavyalova, Elena
author_sort Gribanyov, Dmitry
collection PubMed
description Development of sensitive techniques for rapid detection of viruses is on a high demand. Surface-enhanced Raman spectroscopy (SERS) is an appropriate tool for new techniques due to its high sensitivity. DNA aptamers are short structured oligonucleotides that can provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection had several disadvantages. Some of them lacked possibility of quantitative determination, while others had sophisticated and expensive implementation. In this paper, we provide a new approach that combines rapid specific detection and the possibility of quantitative determination of viruses using the example of influenza A virus.
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spelling pubmed-79185812021-03-02 SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus Gribanyov, Dmitry Zhdanov, Gleb Olenin, Andrei Lisichkin, Georgii Gambaryan, Alexandra Kukushkin, Vladimir Zavyalova, Elena Int J Mol Sci Article Development of sensitive techniques for rapid detection of viruses is on a high demand. Surface-enhanced Raman spectroscopy (SERS) is an appropriate tool for new techniques due to its high sensitivity. DNA aptamers are short structured oligonucleotides that can provide specificity for SERS biosensors. Existing SERS-based aptasensors for rapid virus detection had several disadvantages. Some of them lacked possibility of quantitative determination, while others had sophisticated and expensive implementation. In this paper, we provide a new approach that combines rapid specific detection and the possibility of quantitative determination of viruses using the example of influenza A virus. MDPI 2021-02-12 /pmc/articles/PMC7918581/ /pubmed/33673314 http://dx.doi.org/10.3390/ijms22041842 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gribanyov, Dmitry
Zhdanov, Gleb
Olenin, Andrei
Lisichkin, Georgii
Gambaryan, Alexandra
Kukushkin, Vladimir
Zavyalova, Elena
SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus
title SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus
title_full SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus
title_fullStr SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus
title_full_unstemmed SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus
title_short SERS-Based Colloidal Aptasensors for Quantitative Determination of Influenza Virus
title_sort sers-based colloidal aptasensors for quantitative determination of influenza virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918581/
https://www.ncbi.nlm.nih.gov/pubmed/33673314
http://dx.doi.org/10.3390/ijms22041842
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