Novel Inhibitors of Nicotinamide-N-Methyltransferase for the Treatment of Metabolic Disorders

Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to nicotinamide (Nam). It is expressed in many tissues including the liver, adipose tissue, and skeletal muscle. Its expression in several cancer cell lines has be...

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Detalles Bibliográficos
Autores principales: Kannt, Aimo, Rajagopal, Sridharan, Hallur, Mahanandeesha S., Swamy, Indu, Kristam, Rajendra, Dhakshinamoorthy, Saravanakumar, Czech, Joerg, Zech, Gernot, Schreuder, Herman, Ruf, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918612/
https://www.ncbi.nlm.nih.gov/pubmed/33668468
http://dx.doi.org/10.3390/molecules26040991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918612/
https://www.ncbi.nlm.nih.gov/pubmed/33668468
http://dx.doi.org/10.3390/molecules26040991

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