Cargando…

Tumor Heterogeneity in Glioblastomas: From Light Microscopy to Molecular Pathology

SIMPLE SUMMARY: Glioblastomas (GBMs) are the most frequent and aggressive malignant tumors arising in the human brain. One of the main reasons for GBM aggressiveness is its diverse cellular composition, comprised by differentiated tumor cells, tumor stem cells, cells from the blood vessels, and infl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Becker, Aline P., Sells, Blake E., Haque, S. Jaharul, Chakravarti, Arnab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918815/ https://www.ncbi.nlm.nih.gov/pubmed/33673104 http://dx.doi.org/10.3390/cancers13040761

Ejemplares similares

PATH-15. PROTEOMIC SIGNATURES PREDICT GRADE IN PEDIATRIC AND YOUNG ADULT INFILTRATIVE ASTROCYTOMAS
por: Graham, Richard T, et al.
Publicado: (2020)

Calpastatin phosphorylation regulates radiation-induced calpain activity in glioblastoma
por: Bassett, Emily A., et al.
Publicado: (2018)

HGG-45. PROTEOMIC ANALYSIS OF PEDIATRIC DIFFUSE ASTROCYTOMAS YIELDS PATHWAYS ASSOCIATED WITH BOTH PROGRESSION-FREE AND OVERALL SURVIVAL
por: Sells, Blake, et al.
Publicado: (2020)

The Role of miRNAs in Angiogenesis, Invasion and Metabolism and Their Therapeutic Implications in Gliomas
por: Beyer, Sasha, et al.
Publicado: (2017)

Overcoming Radiation Resistance in Gliomas by Targeting Metabolism and DNA Repair Pathways
por: Meng, Wei, et al.
Publicado: (2022)

BIOL-05. IDENTIFICATION AND VALIDATION OF PA2G4 AS A POTENTIAL THERAPEUTIC TARGET IN PEDIATRIC DIFFUSE GLIOMAS
por: Sirhan, Zaid, et al.
Publicado: (2023)

Triple-Negative Breast Cancer Comparison With Canine Mammary Tumors From Light Microscopy to Molecular Pathology
por: Amirkhani Namagerdi, Asadoor, et al.
Publicado: (2020)

Oncogenic transgelin-2 is differentially regulated in isocitrate dehydrogenase wild-type vs. mutant gliomas
por: Beyer, Sasha J., et al.
Publicado: (2018)

Novel Therapies in Glioblastoma
por: Perry, James, et al.
Publicado: (2012)

p300- and Myc-mediated regulation of glioblastoma multiforme cell differentiation
por: Panicker, Sreejith P., et al.
Publicado: (2010)

Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma
por: DeCordova, Syreeta, et al.
Publicado: (2020)

Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy
por: Ryan, Duncan P., et al.
Publicado: (2017)

Molecular heterogeneity of glioblastomas: does location matter?
por: Denicolaï, Emilie, et al.
Publicado: (2015)

Molecular Heterogeneity in Glioblastoma: Potential Clinical Implications
por: Parker, Nicole Renee, et al.
Publicado: (2015)

Distribution of tumor-infiltrating immune cells in glioblastoma
por: Orrego, Enrique, et al.
Publicado: (2018)

Faster than light (microscopy): superiority of digital pathology over microscopy for assessment of immunohistochemistry
por: Clarke, Emily, et al.
Publicado: (2023)

Diagnostic Pitfalls of Digital Microscopy Versus Light Microscopy in Gastrointestinal Pathology: A Systematic Review
por: Shi, Wangpan, et al.
Publicado: (2021)

Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment
por: Arrieta, Víctor A., et al.
Publicado: (2023)

Tumor Heterogeneity and Molecular Characteristics of Glioblastoma Revealed by Single-Cell RNA-Seq Data Analysis
por: Yesudhas, Dhanusha, et al.
Publicado: (2022)

Biomarkers of Tumor Heterogeneity in Glioblastoma Multiforme Cohort of TCGA
por: Winkelmaier, Garrett, et al.
Publicado: (2023)

Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity
por: Cai, Ling, et al.
Publicado: (2023)

Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas
por: Abou-El-Ardat, Khalil, et al.
Publicado: (2017)

Roles of Chromatin Remodelling and Molecular Heterogeneity in Therapy Resistance in Glioblastoma
por: Chen, Huey-Miin, et al.
Publicado: (2022)

TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways
por: Singh, Karnika, et al.
Publicado: (2023)

The Evidence of Glioblastoma Heterogeneity
por: Soeda, Akio, et al.
Publicado: (2015)

Pathological and Molecular Features of Glioblastoma and Its Peritumoral Tissue
por: D’Alessio, Alessio, et al.
Publicado: (2019)

The Hallmarks of Glioblastoma: Heterogeneity, Intercellular Crosstalk and Molecular Signature of Invasiveness and Progression
por: Torrisi, Filippo, et al.
Publicado: (2022)

Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update
por: Malric, Laure, et al.
Publicado: (2017)

Deconvolution of light sheet microscopy recordings
por: Becker, Klaus, et al.
Publicado: (2019)

MBRS-29. PROSPECTIVE MOLECULAR PROFILING IN PEDIATRIC MEDULLOBLASTOMA PATIENTS ENROLLED ON THE “HEAD START 4” PROTOCOL
por: Fleming, Jessica, et al.
Publicado: (2020)

Light-sheet microscopy for slide-free non-destructive pathology of large clinical specimens
por: Glaser, Adam K., et al.
Publicado: (2017)

Tumor Metabolism of Malignant Gliomas
por: Ru, Peng, et al.
Publicado: (2013)

Measuring dental students’ preference: A comparison of light microscopy and virtual microscopy as teaching tools in oral histology and pathology
por: Alotaibi, Ohoud, et al.
Publicado: (2016)

Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors
por: Schäfer, Niklas, et al.
Publicado: (2019)

Intratumoral heterogeneity of endogenous tumor cell invasive behavior in human glioblastoma
por: Parker, Jonathon J., et al.
Publicado: (2018)

Chemoradiotherapy Increases Intratumor Heterogeneity of HPSE Expression in the Relapsed Glioblastoma Tumors
por: Suhovskih, Anastasia V., et al.
Publicado: (2020)

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
por: Dirkse, Anne, et al.
Publicado: (2019)

CORRIGENDUM: The Evidence of Glioblastoma Heterogeneity
por: Soeda, Akio, et al.
Publicado: (2015)

The prognostic value of nestin expression in newly diagnosed glioblastoma: Report from the Radiation Therapy Oncology Group
por: Chinnaiyan, Prakash, et al.
Publicado: (2008)

Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis
por: Chyra, Zuzana, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k8j1o2muqurumtsvavvu9bgk99