Cargando…
Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering
Three-dimensional (3D) printing is a valuable tool in the production of complexes structures with specific shapes for tissue engineering. Differently from native tissues, the printed structures are static and do not transform their shape in response to different environment changes. Stimuli-responsi...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918883/ https://www.ncbi.nlm.nih.gov/pubmed/33668617 http://dx.doi.org/10.3390/polym13040563 |
_version_ | 1783658024171208704 |
---|---|
author | Saska, Sybele Pilatti, Livia Blay, Alberto Shibli, Jamil Awad |
author_facet | Saska, Sybele Pilatti, Livia Blay, Alberto Shibli, Jamil Awad |
author_sort | Saska, Sybele |
collection | PubMed |
description | Three-dimensional (3D) printing is a valuable tool in the production of complexes structures with specific shapes for tissue engineering. Differently from native tissues, the printed structures are static and do not transform their shape in response to different environment changes. Stimuli-responsive biocompatible materials have emerged in the biomedical field due to the ability of responding to other stimuli (physical, chemical, and/or biological), resulting in microstructures modifications. Four-dimensional (4D) printing arises as a new technology that implements dynamic improvements in printed structures using smart materials (stimuli-responsive materials) and/or cells. These dynamic scaffolds enable engineered tissues to undergo morphological changes in a pre-planned way. Stimuli-responsive polymeric hydrogels are the most promising material for 4D bio-fabrication because they produce a biocompatible and bioresorbable 3D shape environment similar to the extracellular matrix and allow deposition of cells on the scaffold surface as well as in the inside. Subsequently, this review presents different bioresorbable advanced polymers and discusses its use in 4D printing for tissue engineering applications. |
format | Online Article Text |
id | pubmed-7918883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79188832021-03-02 Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering Saska, Sybele Pilatti, Livia Blay, Alberto Shibli, Jamil Awad Polymers (Basel) Review Three-dimensional (3D) printing is a valuable tool in the production of complexes structures with specific shapes for tissue engineering. Differently from native tissues, the printed structures are static and do not transform their shape in response to different environment changes. Stimuli-responsive biocompatible materials have emerged in the biomedical field due to the ability of responding to other stimuli (physical, chemical, and/or biological), resulting in microstructures modifications. Four-dimensional (4D) printing arises as a new technology that implements dynamic improvements in printed structures using smart materials (stimuli-responsive materials) and/or cells. These dynamic scaffolds enable engineered tissues to undergo morphological changes in a pre-planned way. Stimuli-responsive polymeric hydrogels are the most promising material for 4D bio-fabrication because they produce a biocompatible and bioresorbable 3D shape environment similar to the extracellular matrix and allow deposition of cells on the scaffold surface as well as in the inside. Subsequently, this review presents different bioresorbable advanced polymers and discusses its use in 4D printing for tissue engineering applications. MDPI 2021-02-13 /pmc/articles/PMC7918883/ /pubmed/33668617 http://dx.doi.org/10.3390/polym13040563 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Saska, Sybele Pilatti, Livia Blay, Alberto Shibli, Jamil Awad Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering |
title | Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering |
title_full | Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering |
title_fullStr | Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering |
title_full_unstemmed | Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering |
title_short | Bioresorbable Polymers: Advanced Materials and 4D Printing for Tissue Engineering |
title_sort | bioresorbable polymers: advanced materials and 4d printing for tissue engineering |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918883/ https://www.ncbi.nlm.nih.gov/pubmed/33668617 http://dx.doi.org/10.3390/polym13040563 |
work_keys_str_mv | AT saskasybele bioresorbablepolymersadvancedmaterialsand4dprintingfortissueengineering AT pilattilivia bioresorbablepolymersadvancedmaterialsand4dprintingfortissueengineering AT blayalberto bioresorbablepolymersadvancedmaterialsand4dprintingfortissueengineering AT shiblijamilawad bioresorbablepolymersadvancedmaterialsand4dprintingfortissueengineering |