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The Human Gut Microbe Bacteroides thetaiotaomicron Suppresses Toxin Release from Clostridium difficile by Inhibiting Autolysis

Disruption of the human gut microbiota by antibiotics can lead to Clostridium difficile (CD)-associated diarrhea. CD overgrowth and elevated CD toxins result in gut inflammation. Herein, we report that a gut symbiont, Bacteroides thetaiotaomicron (BT), suppressed CD toxin production. The suppressive...

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Detalles Bibliográficos
Autores principales: Elahi, Miad, Nakayama-Imaohji, Haruyuki, Hashimoto, Masahito, Tada, Ayano, Yamasaki, Hisashi, Nagao, Tamiko, Kuwahara, Tomomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918992/
https://www.ncbi.nlm.nih.gov/pubmed/33671889
http://dx.doi.org/10.3390/antibiotics10020187