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Differential Effects of Trp53 Alterations in Murine Colorectal Cancer

SIMPLE SUMMARY: Although colorectal cancer is among the most frequent malignant tumors, there are currently no mouse models available that reliably mimic both tumor biology as well as treatment response. In this article, we describe a novel mouse model in which mutations relevant to colorectal cance...

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Detalles Bibliográficos
Autores principales:	Betzler, Alexander M., Nanduri, Lahiri K., Hissa, Barbara, Blickensdörfer, Linda, Muders, Michael H., Roy, Janine, Jesinghaus, Moritz, Steiger, Katja, Weichert, Wilko, Kloor, Matthias, Klink, Barbara, Schroeder, Michael, Mazzone, Massimiliano, Weitz, Jürgen, Reissfelder, Christoph, Rahbari, Nuh N., Schölch, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919037/ https://www.ncbi.nlm.nih.gov/pubmed/33671932 http://dx.doi.org/10.3390/cancers13040808

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