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HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs

BACKGROUND: Patients with non‐small cell lung cancer (NSCLC) harboring activating EGFR mutations are sensitive to epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐TKIs) but inevitably develop resistance to the inhibitors mostly through acquisition of the secondary T790M mutation. Al...

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Detalles Bibliográficos
Autores principales:	Watanabe, Sho, Goto, Yasushi, Yasuda, Hiroyuki, Kohno, Takashi, Motoi, Noriko, Ohe, Yuichiro, Nishikawa, Hiroyoshi, Kobayashi, Susumu S., Kuwano, Kazuyoshi, Togashi, Yosuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919131/ https://www.ncbi.nlm.nih.gov/pubmed/33471376 http://dx.doi.org/10.1111/1759-7714.13839

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