A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report

BACKGROUND: Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period. CASE PRESENTATION: This study highlights details of treating a COVID-19 pregnant patient who s...

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Autores principales: Aminimoghaddam, Soheila, Afrooz, Narjes, Nasiri, Setare, Motaghi Nejad, Ozra, Mahmoudzadeh, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919244/
https://www.ncbi.nlm.nih.gov/pubmed/33648584
http://dx.doi.org/10.1186/s13256-020-02577-5
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author Aminimoghaddam, Soheila
Afrooz, Narjes
Nasiri, Setare
Motaghi Nejad, Ozra
Mahmoudzadeh, Fatemeh
author_facet Aminimoghaddam, Soheila
Afrooz, Narjes
Nasiri, Setare
Motaghi Nejad, Ozra
Mahmoudzadeh, Fatemeh
author_sort Aminimoghaddam, Soheila
collection PubMed
description BACKGROUND: Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period. CASE PRESENTATION: This study highlights details of treating a COVID-19 pregnant patient who survived. This 21-year addicted White woman was admitted at her 29th week and delivered a stillbirth. She was transferred to another hospital after showing signs of TTP, which was caused by a viral infection. CONCLUSION: This viral infection caused fever and dyspnea, and the patient was tested positive for COVID-19 infection. A chest computed tomography scan showed diffuse multiple bilateral consolidations and interlobar septal thickening. She stayed at the Intensive Care Unit for 20 days and treated with plasmapheresis. As far as we know, this is the first report of a TTP pregnant patient with COVID-19 infection.
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spelling pubmed-79192442021-03-02 A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report Aminimoghaddam, Soheila Afrooz, Narjes Nasiri, Setare Motaghi Nejad, Ozra Mahmoudzadeh, Fatemeh J Med Case Rep Case Report BACKGROUND: Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period. CASE PRESENTATION: This study highlights details of treating a COVID-19 pregnant patient who survived. This 21-year addicted White woman was admitted at her 29th week and delivered a stillbirth. She was transferred to another hospital after showing signs of TTP, which was caused by a viral infection. CONCLUSION: This viral infection caused fever and dyspnea, and the patient was tested positive for COVID-19 infection. A chest computed tomography scan showed diffuse multiple bilateral consolidations and interlobar septal thickening. She stayed at the Intensive Care Unit for 20 days and treated with plasmapheresis. As far as we know, this is the first report of a TTP pregnant patient with COVID-19 infection. BioMed Central 2021-03-01 /pmc/articles/PMC7919244/ /pubmed/33648584 http://dx.doi.org/10.1186/s13256-020-02577-5 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Aminimoghaddam, Soheila
Afrooz, Narjes
Nasiri, Setare
Motaghi Nejad, Ozra
Mahmoudzadeh, Fatemeh
A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
title A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
title_full A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
title_fullStr A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
title_full_unstemmed A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
title_short A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
title_sort covid-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919244/
https://www.ncbi.nlm.nih.gov/pubmed/33648584
http://dx.doi.org/10.1186/s13256-020-02577-5
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