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Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay

P53, P63, and P73 proteins belong to the P53 family of transcription factors, sharing a common gene organization that, from the P1 and P2 promoters, produces two groups of mRNAs encoding proteins with different N-terminal regions; moreover, alternative splicing events at C-terminus further contribut...

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Detalles Bibliográficos
Autores principales:	Monti, Paola, Brazda, Vaclav, Bohálová, Natália, Porubiaková, Otília, Menichini, Paola, Speciale, Andrea, Bocciardi, Renata, Inga, Alberto, Fronza, Gilberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919268/ https://www.ncbi.nlm.nih.gov/pubmed/33672023 http://dx.doi.org/10.3390/genes12020277

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