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Pretibial myxedema in a euthyroid patient: a case report

BACKGROUND: Pretibial myxedema also known as localized myxedema, thyroid dermopathy, or infiltrative dermopathy and rarely as localized mucinosis is an infrequent manifestation of Graves’ disease. It can appear before, during, or after the thyrotoxic state. Euthyroid pretibial myxedema is a rare pre...

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Autores principales: Ambachew, Rediet, Yosef, Tizita, Gebremariam, Aklilu M., Demere, Lishan, Aberra, Theodros, Tarekegn, Getahun, Reja, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919313/
https://www.ncbi.nlm.nih.gov/pubmed/33648506
http://dx.doi.org/10.1186/s13044-021-00096-z
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author Ambachew, Rediet
Yosef, Tizita
Gebremariam, Aklilu M.
Demere, Lishan
Aberra, Theodros
Tarekegn, Getahun
Reja, Ahmed
author_facet Ambachew, Rediet
Yosef, Tizita
Gebremariam, Aklilu M.
Demere, Lishan
Aberra, Theodros
Tarekegn, Getahun
Reja, Ahmed
author_sort Ambachew, Rediet
collection PubMed
description BACKGROUND: Pretibial myxedema also known as localized myxedema, thyroid dermopathy, or infiltrative dermopathy and rarely as localized mucinosis is an infrequent manifestation of Graves’ disease. It can appear before, during, or after the thyrotoxic state. Euthyroid pretibial myxedema is a rare presentation with few case reports in the literature. This case highlights the importance of considering pretibial myxedema when characteristic skin lesions are observed in a euthyroid patient. CASE PRESENTATION: A 72-year old male Ethiopian patient with a very rare presentation of biopsy-proven pretibial myxedema in a euthyroid state without history of thyroid disease and absence of thyroid autoimmune markers. Resolution of skin lesion was achieved after topical corticosteroid application. CONCLUSION: Absence of history of thyroid disorder and normal thyroid function tests should not exclude the diagnosis of pretibial myxedema.
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spelling pubmed-79193132021-03-02 Pretibial myxedema in a euthyroid patient: a case report Ambachew, Rediet Yosef, Tizita Gebremariam, Aklilu M. Demere, Lishan Aberra, Theodros Tarekegn, Getahun Reja, Ahmed Thyroid Res Case Report BACKGROUND: Pretibial myxedema also known as localized myxedema, thyroid dermopathy, or infiltrative dermopathy and rarely as localized mucinosis is an infrequent manifestation of Graves’ disease. It can appear before, during, or after the thyrotoxic state. Euthyroid pretibial myxedema is a rare presentation with few case reports in the literature. This case highlights the importance of considering pretibial myxedema when characteristic skin lesions are observed in a euthyroid patient. CASE PRESENTATION: A 72-year old male Ethiopian patient with a very rare presentation of biopsy-proven pretibial myxedema in a euthyroid state without history of thyroid disease and absence of thyroid autoimmune markers. Resolution of skin lesion was achieved after topical corticosteroid application. CONCLUSION: Absence of history of thyroid disorder and normal thyroid function tests should not exclude the diagnosis of pretibial myxedema. BioMed Central 2021-03-01 /pmc/articles/PMC7919313/ /pubmed/33648506 http://dx.doi.org/10.1186/s13044-021-00096-z Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Ambachew, Rediet
Yosef, Tizita
Gebremariam, Aklilu M.
Demere, Lishan
Aberra, Theodros
Tarekegn, Getahun
Reja, Ahmed
Pretibial myxedema in a euthyroid patient: a case report
title Pretibial myxedema in a euthyroid patient: a case report
title_full Pretibial myxedema in a euthyroid patient: a case report
title_fullStr Pretibial myxedema in a euthyroid patient: a case report
title_full_unstemmed Pretibial myxedema in a euthyroid patient: a case report
title_short Pretibial myxedema in a euthyroid patient: a case report
title_sort pretibial myxedema in a euthyroid patient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919313/
https://www.ncbi.nlm.nih.gov/pubmed/33648506
http://dx.doi.org/10.1186/s13044-021-00096-z
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