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Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method

BACKGROUND: Liver cancer is the sixth most common cancer worldwide. It is mostly diagnosed with a computed tomography scan. Nowadays deep learning methods have been used for the segmentation of the liver and its tumor from the computed tomography (CT) scan images. This research mainly focused on seg...

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Autores principales: Ayalew, Yodit Abebe, Fante, Kinde Anlay, Mohammed, Mohammed Aliy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919329/
https://www.ncbi.nlm.nih.gov/pubmed/33641679
http://dx.doi.org/10.1186/s42490-021-00050-y
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author Ayalew, Yodit Abebe
Fante, Kinde Anlay
Mohammed, Mohammed Aliy
author_facet Ayalew, Yodit Abebe
Fante, Kinde Anlay
Mohammed, Mohammed Aliy
author_sort Ayalew, Yodit Abebe
collection PubMed
description BACKGROUND: Liver cancer is the sixth most common cancer worldwide. It is mostly diagnosed with a computed tomography scan. Nowadays deep learning methods have been used for the segmentation of the liver and its tumor from the computed tomography (CT) scan images. This research mainly focused on segmenting liver and tumor from the abdominal CT scan images using a deep learning method and minimizing the effort and time used for a liver cancer diagnosis. The algorithm is based on the original UNet architecture. But, here in this paper, the numbers of filters on each convolutional block were reduced and new batch normalization and a dropout layer were added after each convolutional block of the contracting path. RESULTS: Using this algorithm a dice score of 0.96, 0.74, and 0.63 were obtained for liver segmentation, segmentation of tumors from the liver, and the segmentation of tumor from abdominal CT scan images respectively. The segmentation results of liver and tumor from the liver showed an improvement of 0.01 and 0.11 respectively from other works. CONCLUSION: This work proposed a liver and a tumor segmentation method using a UNet architecture as a baseline. Modification regarding the number of filters and network layers were done on the original UNet model to reduce the network complexity and improve segmentation performance. A new class balancing method is also introduced to minimize the class imbalance problem. Through these, the algorithm attained better segmentation results and showed good improvement. However, it faced difficulty in segmenting small and irregular tumors.
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spelling pubmed-79193292021-03-02 Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method Ayalew, Yodit Abebe Fante, Kinde Anlay Mohammed, Mohammed Aliy BMC Biomed Eng Research Article BACKGROUND: Liver cancer is the sixth most common cancer worldwide. It is mostly diagnosed with a computed tomography scan. Nowadays deep learning methods have been used for the segmentation of the liver and its tumor from the computed tomography (CT) scan images. This research mainly focused on segmenting liver and tumor from the abdominal CT scan images using a deep learning method and minimizing the effort and time used for a liver cancer diagnosis. The algorithm is based on the original UNet architecture. But, here in this paper, the numbers of filters on each convolutional block were reduced and new batch normalization and a dropout layer were added after each convolutional block of the contracting path. RESULTS: Using this algorithm a dice score of 0.96, 0.74, and 0.63 were obtained for liver segmentation, segmentation of tumors from the liver, and the segmentation of tumor from abdominal CT scan images respectively. The segmentation results of liver and tumor from the liver showed an improvement of 0.01 and 0.11 respectively from other works. CONCLUSION: This work proposed a liver and a tumor segmentation method using a UNet architecture as a baseline. Modification regarding the number of filters and network layers were done on the original UNet model to reduce the network complexity and improve segmentation performance. A new class balancing method is also introduced to minimize the class imbalance problem. Through these, the algorithm attained better segmentation results and showed good improvement. However, it faced difficulty in segmenting small and irregular tumors. BioMed Central 2021-03-01 /pmc/articles/PMC7919329/ /pubmed/33641679 http://dx.doi.org/10.1186/s42490-021-00050-y Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Ayalew, Yodit Abebe
Fante, Kinde Anlay
Mohammed, Mohammed Aliy
Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method
title Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method
title_full Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method
title_fullStr Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method
title_full_unstemmed Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method
title_short Modified U-Net for liver cancer segmentation from computed tomography images with a new class balancing method
title_sort modified u-net for liver cancer segmentation from computed tomography images with a new class balancing method
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919329/
https://www.ncbi.nlm.nih.gov/pubmed/33641679
http://dx.doi.org/10.1186/s42490-021-00050-y
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