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Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway

Overuse of acetaminophen (APAP) is a major cause of drug-induced liver failure at the clinics. Apigenin (API) is a natural flavonoid derived from Matricaria chamomilla. The aim of the present study was to investigate the amelioration function of API in APAP-induced hepatotoxicity both in vitro and i...

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Detalles Bibliográficos
Autores principales: Zhang, Jiaqi, Liang, Xiaoqiang, Li, Jiacheng, Yin, Hao, Liu, Fangchen, Hu, Cheng, Li, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919381/
https://www.ncbi.nlm.nih.gov/pubmed/33658919
http://dx.doi.org/10.3389/fphar.2020.549057

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