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Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway
Overuse of acetaminophen (APAP) is a major cause of drug-induced liver failure at the clinics. Apigenin (API) is a natural flavonoid derived from Matricaria chamomilla. The aim of the present study was to investigate the amelioration function of API in APAP-induced hepatotoxicity both in vitro and i...
Autores principales: | Zhang, Jiaqi, Liang, Xiaoqiang, Li, Jiacheng, Yin, Hao, Liu, Fangchen, Hu, Cheng, Li, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919381/ https://www.ncbi.nlm.nih.gov/pubmed/33658919 http://dx.doi.org/10.3389/fphar.2020.549057 |
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