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Rtt109 slows replication speed by histone N-terminal acetylation

The wrapping of DNA around histone octamers challenges processes that use DNA as their template. In vitro, DNA replication through chromatin depends on histone modifiers, raising the possibility that cells modify histones to optimize fork progression. Rtt109 is an acetyl transferase that acetylates...

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Detalles Bibliográficos
Autores principales: Frenkel, Nelly, Jonas, Felix, Carmi, Miri, Yaakov, Gilad, Barkai, Naama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919450/
https://www.ncbi.nlm.nih.gov/pubmed/33563717
http://dx.doi.org/10.1101/gr.266510.120

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