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Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection?
We describe a unique case of fulminant myocarditis in a patient with presumed SARS-CoV-2 reinfection. Patient had initial infection 4 months backand had COVID-19 antibody at the time of presentation. Endomyocardial biopsy showed lymphocytic myocarditis, that is usually seen in viral myocarditis. The...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919708/ https://www.ncbi.nlm.nih.gov/pubmed/33615872 http://dx.doi.org/10.2217/fca-2020-0237 |
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author | Yeleti, Ramya Guglin, Maya Saleem, Kashif Adigopula, Sasikanth V Sinha, Anjan Upadhyay, Smrity Everett, Jeffrey E Ballut, Kareem Uppuluri, Sarada Rao, Roopa A |
author_facet | Yeleti, Ramya Guglin, Maya Saleem, Kashif Adigopula, Sasikanth V Sinha, Anjan Upadhyay, Smrity Everett, Jeffrey E Ballut, Kareem Uppuluri, Sarada Rao, Roopa A |
author_sort | Yeleti, Ramya |
collection | PubMed |
description | We describe a unique case of fulminant myocarditis in a patient with presumed SARS-CoV-2 reinfection. Patient had initial infection 4 months backand had COVID-19 antibody at the time of presentation. Endomyocardial biopsy showed lymphocytic myocarditis, that is usually seen in viral myocarditis. The molecular diagnostic testing of the endomyocardial biopsy for cardiotropic viruses was positive for Parvovirus and negative for SARS-CoV-2. Authors highly suspect co-infection of SARS-CoV-2 and Parvovirus, that possibly triggered the immune cascade resulting in fulminant myocarditis. Patient was hemodynamically unstable with ventricular tachycardia and was supported on VA ECMO and Impella CP. There was impressive recovery of left ventricular function within 48 hours, leading to decannulation of VA ECMO in 72 h. This unique case was written by the survivor herself. |
format | Online Article Text |
id | pubmed-7919708 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-79197082021-03-01 Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? Yeleti, Ramya Guglin, Maya Saleem, Kashif Adigopula, Sasikanth V Sinha, Anjan Upadhyay, Smrity Everett, Jeffrey E Ballut, Kareem Uppuluri, Sarada Rao, Roopa A Future Cardiol Case Report We describe a unique case of fulminant myocarditis in a patient with presumed SARS-CoV-2 reinfection. Patient had initial infection 4 months backand had COVID-19 antibody at the time of presentation. Endomyocardial biopsy showed lymphocytic myocarditis, that is usually seen in viral myocarditis. The molecular diagnostic testing of the endomyocardial biopsy for cardiotropic viruses was positive for Parvovirus and negative for SARS-CoV-2. Authors highly suspect co-infection of SARS-CoV-2 and Parvovirus, that possibly triggered the immune cascade resulting in fulminant myocarditis. Patient was hemodynamically unstable with ventricular tachycardia and was supported on VA ECMO and Impella CP. There was impressive recovery of left ventricular function within 48 hours, leading to decannulation of VA ECMO in 72 h. This unique case was written by the survivor herself. Future Medicine Ltd 2021-02-22 2021-01 /pmc/articles/PMC7919708/ /pubmed/33615872 http://dx.doi.org/10.2217/fca-2020-0237 Text en © 2021 Future Medicine Ltd This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Case Report Yeleti, Ramya Guglin, Maya Saleem, Kashif Adigopula, Sasikanth V Sinha, Anjan Upadhyay, Smrity Everett, Jeffrey E Ballut, Kareem Uppuluri, Sarada Rao, Roopa A Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? |
title | Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? |
title_full | Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? |
title_fullStr | Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? |
title_full_unstemmed | Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? |
title_short | Fulminant myocarditis: COVID or not COVID? Reinfection or co-infection? |
title_sort | fulminant myocarditis: covid or not covid? reinfection or co-infection? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919708/ https://www.ncbi.nlm.nih.gov/pubmed/33615872 http://dx.doi.org/10.2217/fca-2020-0237 |
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