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An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics

The coronavirus disease 19 (COVID-19) pandemic is having a dramatic impact on society and healthcare systems. In this complex scenario, lung computerized tomography (CT) may play an important prognostic role. However, datasets released so far present limitations that hamper the development of tools...

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Autores principales: Zaffino, Paolo, Marzullo, Aldo, Moccia, Sara, Calimeri, Francesco, De Momi, Elena, Bertucci, Bernardo, Arcuri, Pier Paolo, Spadea, Maria Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919807/
https://www.ncbi.nlm.nih.gov/pubmed/33669235
http://dx.doi.org/10.3390/bioengineering8020026
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author Zaffino, Paolo
Marzullo, Aldo
Moccia, Sara
Calimeri, Francesco
De Momi, Elena
Bertucci, Bernardo
Arcuri, Pier Paolo
Spadea, Maria Francesca
author_facet Zaffino, Paolo
Marzullo, Aldo
Moccia, Sara
Calimeri, Francesco
De Momi, Elena
Bertucci, Bernardo
Arcuri, Pier Paolo
Spadea, Maria Francesca
author_sort Zaffino, Paolo
collection PubMed
description The coronavirus disease 19 (COVID-19) pandemic is having a dramatic impact on society and healthcare systems. In this complex scenario, lung computerized tomography (CT) may play an important prognostic role. However, datasets released so far present limitations that hamper the development of tools for quantitative analysis. In this paper, we present an open-source lung CT dataset comprising information on 50 COVID-19-positive patients. The CT volumes are provided along with (i) an automatic threshold-based annotation obtained with a Gaussian mixture model (GMM) and (ii) a scoring provided by an expert radiologist. This score was found to significantly correlate with the presence of ground glass opacities and the consolidation found with GMM. The dataset is freely available in an ITK-based file format under the CC BY-NC 4.0 license. The code for GMM fitting is publicly available, as well. We believe that our dataset will provide a unique opportunity for researchers working in the field of medical image analysis, and hope that its release will lay the foundations for the successfully implementation of algorithms to support clinicians in facing the COVID-19 pandemic.
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spelling pubmed-79198072021-03-02 An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics Zaffino, Paolo Marzullo, Aldo Moccia, Sara Calimeri, Francesco De Momi, Elena Bertucci, Bernardo Arcuri, Pier Paolo Spadea, Maria Francesca Bioengineering (Basel) Article The coronavirus disease 19 (COVID-19) pandemic is having a dramatic impact on society and healthcare systems. In this complex scenario, lung computerized tomography (CT) may play an important prognostic role. However, datasets released so far present limitations that hamper the development of tools for quantitative analysis. In this paper, we present an open-source lung CT dataset comprising information on 50 COVID-19-positive patients. The CT volumes are provided along with (i) an automatic threshold-based annotation obtained with a Gaussian mixture model (GMM) and (ii) a scoring provided by an expert radiologist. This score was found to significantly correlate with the presence of ground glass opacities and the consolidation found with GMM. The dataset is freely available in an ITK-based file format under the CC BY-NC 4.0 license. The code for GMM fitting is publicly available, as well. We believe that our dataset will provide a unique opportunity for researchers working in the field of medical image analysis, and hope that its release will lay the foundations for the successfully implementation of algorithms to support clinicians in facing the COVID-19 pandemic. MDPI 2021-02-16 /pmc/articles/PMC7919807/ /pubmed/33669235 http://dx.doi.org/10.3390/bioengineering8020026 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zaffino, Paolo
Marzullo, Aldo
Moccia, Sara
Calimeri, Francesco
De Momi, Elena
Bertucci, Bernardo
Arcuri, Pier Paolo
Spadea, Maria Francesca
An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics
title An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics
title_full An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics
title_fullStr An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics
title_full_unstemmed An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics
title_short An Open-Source COVID-19 CT Dataset with Automatic Lung Tissue Classification for Radiomics
title_sort open-source covid-19 ct dataset with automatic lung tissue classification for radiomics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919807/
https://www.ncbi.nlm.nih.gov/pubmed/33669235
http://dx.doi.org/10.3390/bioengineering8020026
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