Cargando…

Single-cell map of diverse immune phenotypes in the acute myeloid leukemia microenvironment

BACKGROUND: Knowledge of immune cell phenotypes, function, and developmental trajectory in acute myeloid leukemia (AML) microenvironment is essential for understanding mechanisms of evading immune surveillance and immunotherapy response of targeting special microenvironment components. METHODS: Usin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Rongqun, Lü, Mengdie, Cao, Fujiao, Wu, Guanghua, Gao, Fengcai, Pang, Haili, Li, Yadan, Zhang, Yinyin, Xing, Haizhou, Liang, Chunyan, Lyu, Tianxin, Du, Chunyan, Li, Yingmei, Guo, Rong, Xie, Xinsheng, Li, Wei, Liu, Delong, Song, Yongping, Jiang, Zhongxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919996/ https://www.ncbi.nlm.nih.gov/pubmed/33648605 http://dx.doi.org/10.1186/s40364-021-00265-0

Ejemplares similares

Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells
por: Guo, Rongqun, et al.
Publicado: (2022)

Single-Cell Analysis of Target Antigens of CAR-T Reveals a Potential Landscape of “On-Target, Off-Tumor Toxicity”
por: Zhang, Yinyin, et al.
Publicado: (2021)

Evidence of pyroptosis and ferroptosis extensively involved in autoimmune diseases at the single-cell transcriptome level
por: Zhang, Danfeng, et al.
Publicado: (2022)

Deficient Regulatory Innate Lymphoid Cells and Differential Expression of miRNAs in Acute Myeloid Leukemia Quantified by Next Generation Sequence
por: Yu, Jifeng, et al.
Publicado: (2019)

GM-CSF impairs erythropoiesis by disrupting erythroblastic island formation via macrophages
por: Cao, Weijie, et al.
Publicado: (2022)

Exosomes from BM-MSCs promote acute myeloid leukemia cell proliferation, invasion and chemoresistance via upregulation of S100A4
por: Lyu, Tianxin, et al.
Publicado: (2021)

Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia
por: Yu, Jifeng, et al.
Publicado: (2020)

Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic Diseases
por: Li, Wei, et al.
Publicado: (2021)

Corrigendum: Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic Diseases
por: Li, Wei, et al.
Publicado: (2022)

Advances in targeted therapy for acute myeloid leukemia
por: Yu, Jifeng, et al.
Publicado: (2020)

Clinical characteristics, treatment, and prognosis of 118 cases of myeloid sarcoma
por: Zhao, Haiqiu, et al.
Publicado: (2022)

Claudin18.2 is a novel molecular biomarker for tumor-targeted immunotherapy
por: Cao, Weijie, et al.
Publicado: (2022)

Clinical implications of recurrent gene mutations in acute myeloid leukemia
por: Yu, Jifeng, et al.
Publicado: (2020)

Single-cell expression profiles of ACE2 and TMPRSS2 reveals potential vertical transmission and fetus infection of SARS-CoV-2
por: Lü, Mengdie, et al.
Publicado: (2020)

Clinical Characteristics And Outcome Of Biphenotypic Acute Leukemia: 10 Case Reports And Literature Review
por: Yu, Jifeng, et al.
Publicado: (2019)

Ferroptosis in acute leukemia
por: Lyu, Tianxin, et al.
Publicado: (2023)

Prognostic prediction of novel risk scores (AML-DRG and AML-HCT-CR) in acute myeloid leukemia patients with allogeneic hematopoietic stem cell transplantation
por: Cao, Weijie, et al.
Publicado: (2022)

Neuropathy correlated with imbalanced Foxp3/IL-17 in bone marrow microenvironment of patients with acute myeloid leukemia
por: Chen, Chen, et al.
Publicado: (2016)

Mesenchymal stroma/stem‐like cells of GARP knockdown inhibits cell proliferation and invasion of mouse colon cancer cells (MC38) through exosomes
por: Xing, Haizhou, et al.
Publicado: (2020)

Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia
por: Zhao, Juanjuan, et al.
Publicado: (2019)

Mutational spectrum and prognosis in NRAS-mutated acute myeloid leukemia
por: Wang, Shujuan, et al.
Publicado: (2020)

Correction to: Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia
por: Zhao, Juanjuan, et al.
Publicado: (2019)

Quantitative histology analysis of the ovarian tumour microenvironment
por: Lan, Chunyan, et al.
Publicado: (2015)

Targeting macrophages in hematological malignancies: recent advances and future directions
por: Li, Wei, et al.
Publicado: (2022)

Aberrant T Helper 17 Cells and Related Cytokines in Bone Marrow Microenvironment of Patients with Acute Myeloid Leukemia
por: Tian, Tian, et al.
Publicado: (2013)

Decitabine combined with CAG regimen in the treatment of elderly patients with acute myeloid leukemia
por: Zhao, Haitao, et al.
Publicado: (2020)

A 10-Long Non-Coding RNA-Based Expression Signature as a Potential Biomarker for Prognosis of Acute Myeloid Leukemia
por: Tang, Ping, et al.
Publicado: (2019)

Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer
por: Heindl, Andreas, et al.
Publicado: (2016)

Contributions of bone marrow monocytes/macrophages in myeloproliferative neoplasms with JAK2(V617F) mutation
por: Fan, Wenjuan, et al.
Publicado: (2023)

Identification of potential resistance mechanisms and therapeutic targets for the relapse of BCMA CAR-T therapy in relapsed/refractory multiple myeloma through single-cell sequencing
por: Li, Wei, et al.
Publicado: (2023)

The Profile of T Helper Subsets in Bone Marrow Microenvironment Is Distinct for Different Stages of Acute Myeloid Leukemia Patients and Chemotherapy Partly Ameliorates These Variations
por: Tian, Tian, et al.
Publicado: (2015)

The immunometabolic landscape of the bone marrow microenvironment in acute myeloid leukemia
por: Xu, Binyan, et al.
Publicado: (2022)

Correction: Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives
por: Sun, Hao, et al.
Publicado: (2022)

Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives
por: Sun, Hao, et al.
Publicado: (2022)

Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation
por: Ai, Lisha, et al.
Publicado: (2019)

Research progress on exosomes derived from mesenchymal stem cells in hematological malignancies
por: Lyu, Tianxin, et al.
Publicado: (2020)

Immune checkpoint‐related gene polymorphisms are associated with acute myeloid leukemia
por: Wu, Yuyan, et al.
Publicado: (2023)

The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease
por: Li, Chunyan, et al.
Publicado: (2022)

Redirecting the Immune Microenvironment in Acute Myeloid Leukemia
por: Sendker, Stephanie, et al.
Publicado: (2021)

Myeloid cells in COVID-19 microenvironment
por: Qin, Guohui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5ndjk9d3r2poddnsfbqoh4te8f