Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin–Kallikrein System in Severe COVID-19

Background: Coronavirus disease 19 (COVID-19) can develop into a severe respiratory syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major pathological finding in autopsies explaining O(2) diffusion failure and hypoxemia. Only dexamethasone has been shown to reduce mo...

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Detalles Bibliográficos
Autores principales: Mansour, Eli, Palma, Andre C., Ulaf, Raisa G., Ribeiro, Luciana C., Bernardes, Ana Flavia, Nunes, Thyago A., Agrela, Marcus V., Bombassaro, Bruna, Monfort-Pires, Milena, Camargo, Rafael L., Araujo, Eliana P., Brunetti, Natalia S., Farias, Alessandro S., Falcão, Antônio Luís E., Santos, Thiago Martins, Trabasso, Plinio, Dertkigil, Rachel P., Dertkigil, Sergio S., Moretti, Maria Luiza, Velloso, Licio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920028/
https://www.ncbi.nlm.nih.gov/pubmed/33669276
http://dx.doi.org/10.3390/v13020309

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