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Transmucosal Solid Lipid Nanoparticles to Improve Genistein Absorption via Intestinal Lymphatic Transport

Genistein (GEN) is a soy-derived isoflavone that exhibits several biological effects, such as neuroprotective activity and the prevention of several types of cancer and cardiovascular disease. However, due to its poor water solubility and the extensive first-pass metabolism, the oral bioavailability...

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Detalles Bibliográficos
Autores principales: Obinu, Antonella, Burrai, Giovanni Pietro, Cavalli, Roberta, Galleri, Grazia, Migheli, Rossana, Antuofermo, Elisabetta, Rassu, Giovanna, Gavini, Elisabetta, Giunchedi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920073/
https://www.ncbi.nlm.nih.gov/pubmed/33669306
http://dx.doi.org/10.3390/pharmaceutics13020267