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Transmucosal Solid Lipid Nanoparticles to Improve Genistein Absorption via Intestinal Lymphatic Transport
Genistein (GEN) is a soy-derived isoflavone that exhibits several biological effects, such as neuroprotective activity and the prevention of several types of cancer and cardiovascular disease. However, due to its poor water solubility and the extensive first-pass metabolism, the oral bioavailability...
Autores principales: | Obinu, Antonella, Burrai, Giovanni Pietro, Cavalli, Roberta, Galleri, Grazia, Migheli, Rossana, Antuofermo, Elisabetta, Rassu, Giovanna, Gavini, Elisabetta, Giunchedi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920073/ https://www.ncbi.nlm.nih.gov/pubmed/33669306 http://dx.doi.org/10.3390/pharmaceutics13020267 |
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