Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia

Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia...

Descripción completa

Detalles Bibliográficos
Autores principales: Fasulo, Sydney M, Narvaneni, Spandana, Kumar, Vinod, Manje Gowda, Anusha, Sultana, Yasmeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Radiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920237/
https://www.ncbi.nlm.nih.gov/pubmed/33659114
http://dx.doi.org/10.7759/cureus.12959
_version_ 1783658234930790400
author Fasulo, Sydney M
Narvaneni, Spandana
Kumar, Vinod
Manje Gowda, Anusha
Sultana, Yasmeen
author_facet Fasulo, Sydney M
Narvaneni, Spandana
Kumar, Vinod
Manje Gowda, Anusha
Sultana, Yasmeen
author_sort Fasulo, Sydney M
collection PubMed
description Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia, thrombocytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic bone lesion who was diagnosed with HCL.
format Online
Article
Text
id pubmed-7920237
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-79202372021-03-02 Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia Fasulo, Sydney M Narvaneni, Spandana Kumar, Vinod Manje Gowda, Anusha Sultana, Yasmeen Cureus Radiology Hairy cell leukemia (HCL) is a seldom encountered malignancy of lymphocytes with a low incidence in the United States. HCL generally follows an indolent course and not all patients require treatment. Most patients are asymptomatic at the time of diagnosis. Treatment is reserved for those with anemia, thrombocytopenia, neutropenia, recurrent infections, symptomatic splenomegaly, or lymphadenopathy impairing vital organ function. Purine analogs are the mainstay of treatment with a durable response. We report a case of a 49-year old Ukrainian male who presented with bone pain secondary to a lytic bone lesion who was diagnosed with HCL. Cureus 2021-01-28 /pmc/articles/PMC7920237/ /pubmed/33659114 http://dx.doi.org/10.7759/cureus.12959 Text en Copyright © 2021, Fasulo et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiology
Fasulo, Sydney M
Narvaneni, Spandana
Kumar, Vinod
Manje Gowda, Anusha
Sultana, Yasmeen
Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
title Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
title_full Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
title_fullStr Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
title_full_unstemmed Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
title_short Lytic Bone Lesion: An Unusual Presentation of Hairy Cell Leukemia
title_sort lytic bone lesion: an unusual presentation of hairy cell leukemia
topic Radiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920237/
https://www.ncbi.nlm.nih.gov/pubmed/33659114
http://dx.doi.org/10.7759/cureus.12959
work_keys_str_mv AT fasulosydneym lyticbonelesionanunusualpresentationofhairycellleukemia
AT narvanenispandana lyticbonelesionanunusualpresentationofhairycellleukemia
AT kumarvinod lyticbonelesionanunusualpresentationofhairycellleukemia
AT manjegowdaanusha lyticbonelesionanunusualpresentationofhairycellleukemia
AT sultanayasmeen lyticbonelesionanunusualpresentationofhairycellleukemia

Ejemplares similares