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The Multi-Targeting Ligand ST-2223 with Histamine H(3) Receptor and Dopamine D(2)/D(3) Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice

Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder characterized by social and communicative impairments, as well as repetitive and restricted behaviors (RRBs). With the limited effectiveness of current pharmacotherapies in treating repetitive behaviors, the presen...

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Detalles Bibliográficos
Autores principales: Eissa, Nermin, Venkatachalam, Karthikkumar, Jayaprakash, Petrilla, Falkenstein, Markus, Dubiel, Mariam, Frank, Annika, Reiner-Link, David, Stark, Holger, Sadek, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920280/
https://www.ncbi.nlm.nih.gov/pubmed/33669336
http://dx.doi.org/10.3390/ijms22041947

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