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The Multi-Targeting Ligand ST-2223 with Histamine H(3) Receptor and Dopamine D(2)/D(3) Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice
Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder characterized by social and communicative impairments, as well as repetitive and restricted behaviors (RRBs). With the limited effectiveness of current pharmacotherapies in treating repetitive behaviors, the presen...
Autores principales: | Eissa, Nermin, Venkatachalam, Karthikkumar, Jayaprakash, Petrilla, Falkenstein, Markus, Dubiel, Mariam, Frank, Annika, Reiner-Link, David, Stark, Holger, Sadek, Bassem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920280/ https://www.ncbi.nlm.nih.gov/pubmed/33669336 http://dx.doi.org/10.3390/ijms22041947 |
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