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Intestinal Goblet Cell Loss during Chorioamnionitis in Fetal Lambs: Mechanistic Insights and Postnatal Implications
Chorioamnionitis, an important cause of preterm birth, is linked to necrotizing enterocolitis (NEC). NEC is characterized by a disrupted mucus barrier, goblet cell loss, and endoplasmic reticulum (ER) stress of the intestinal epithelium. These findings prompted us to investigate the mechanisms under...
Autores principales: | van Gorp, Charlotte, de Lange, Ilse H., Massy, Kimberly R. I., Kessels, Lilian, Jobe, Alan H., Cleutjens, Jack P. M., Kemp, Matthew W., Saito, Masatoshi, Usada, Haruo, Newnham, John, Hütten, Matthias, Kramer, Boris W., Zimmermann, Luc J., Wolfs, Tim G. A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920290/ https://www.ncbi.nlm.nih.gov/pubmed/33669331 http://dx.doi.org/10.3390/ijms22041946 |
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