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Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations
Narcotic drugs are often used to treat perioperative pain for patients with lung cancer. However, anesthetic management and narcotic substance use may have significant impacts on patients with lung cancer, including anti-cancer or promoting cancer effects. In this study, we summarize the effects of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920500/ https://www.ncbi.nlm.nih.gov/pubmed/33658765 http://dx.doi.org/10.2147/DDDT.S297200 |
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author | Wang, Jian Liu, Lei Song, Yuli Jiao, Jinghua Zhong, Yifan |
author_facet | Wang, Jian Liu, Lei Song, Yuli Jiao, Jinghua Zhong, Yifan |
author_sort | Wang, Jian |
collection | PubMed |
description | Narcotic drugs are often used to treat perioperative pain for patients with lung cancer. However, anesthetic management and narcotic substance use may have significant impacts on patients with lung cancer, including anti-cancer or promoting cancer effects. In this study, we summarize the effects of anesthetic management and its related substances on lung cancer. An evidence-based review of the influence of anesthetic techniques and narcotic substances used on lung cancer was performed. The effects of perioperative pain management and the method of choosing anesthesia for patients with lung cancer were explored. Different management techniques of anesthesia have been indicated to suppress both cell-mediated immunity and humoral immunity and have effects on the recurrence and metastasis of lung cancer. Evidence suggests that the effects of narcotic substances used on lung cancer were still inconsistent. However, the mechanisms by which anesthetics and analgesics inhibit the tumor are complicated. Perioperative management leads to decreased immunity in patients with lung cancer, which to some extent contributes to recurrence and metastasis. Various narcotic substances used may modulate signal pathways, including the mitochondrial pathway, and appear to exert different effects on the recurrence and metastasis of lung cancer. The anesthesiologists should consider these effects on perioperative management with lung cancer. |
format | Online Article Text |
id | pubmed-7920500 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-79205002021-03-02 Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations Wang, Jian Liu, Lei Song, Yuli Jiao, Jinghua Zhong, Yifan Drug Des Devel Ther Review Narcotic drugs are often used to treat perioperative pain for patients with lung cancer. However, anesthetic management and narcotic substance use may have significant impacts on patients with lung cancer, including anti-cancer or promoting cancer effects. In this study, we summarize the effects of anesthetic management and its related substances on lung cancer. An evidence-based review of the influence of anesthetic techniques and narcotic substances used on lung cancer was performed. The effects of perioperative pain management and the method of choosing anesthesia for patients with lung cancer were explored. Different management techniques of anesthesia have been indicated to suppress both cell-mediated immunity and humoral immunity and have effects on the recurrence and metastasis of lung cancer. Evidence suggests that the effects of narcotic substances used on lung cancer were still inconsistent. However, the mechanisms by which anesthetics and analgesics inhibit the tumor are complicated. Perioperative management leads to decreased immunity in patients with lung cancer, which to some extent contributes to recurrence and metastasis. Various narcotic substances used may modulate signal pathways, including the mitochondrial pathway, and appear to exert different effects on the recurrence and metastasis of lung cancer. The anesthesiologists should consider these effects on perioperative management with lung cancer. Dove 2021-02-25 /pmc/articles/PMC7920500/ /pubmed/33658765 http://dx.doi.org/10.2147/DDDT.S297200 Text en © 2021 Wang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Wang, Jian Liu, Lei Song, Yuli Jiao, Jinghua Zhong, Yifan Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations |
title | Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations |
title_full | Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations |
title_fullStr | Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations |
title_full_unstemmed | Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations |
title_short | Current Understanding on Perioperative Management in Lung Cancer: Implications for Anesthetic Considerations |
title_sort | current understanding on perioperative management in lung cancer: implications for anesthetic considerations |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920500/ https://www.ncbi.nlm.nih.gov/pubmed/33658765 http://dx.doi.org/10.2147/DDDT.S297200 |
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