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Novel Resistance Mechanisms to Osimertinib Analysed by Whole-Exome Sequencing in Non-Small Cell Lung Cancer

PURPOSE: Molecular-based targeted therapy has improved life expectancy for advanced non-small cell lung cancer (NSCLC). However, it does not have to be inevitable that patients receiving third-generation EGFR-TKIs become drug resistant. EGFR C797S and MET amplification are common mechanisms of osime...

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Detalles Bibliográficos
Autores principales:	Wu, Zhen, Zhao, Wei, Yang, Zhen, Wang, Yue Ming, Dai, Yu, Chen, Liang-An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920504/ https://www.ncbi.nlm.nih.gov/pubmed/33658860 http://dx.doi.org/10.2147/CMAR.S292342

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