The Combination Therapy of Fluorouracil and Oxaliplatin Suppress the Progression of Colon Cancer Through miR-183-5p/SOCS3 Axis and Downregulating PD-L1

PURPOSE: The purpose of this study was to investigate the mechanism of combination of fluorouracil (FU) and oxaliplatin (OXA) on the progression of colon cancer via miR-183-5p/SOCS3 axis and regulating PD-L1. METHODS: HCT116 cells were treated with 4 μM OXA and 10.5 μM FU, or exogenous regulation of...

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Detalles Bibliográficos
Autores principales: Tu, Changling, Wang, Yufeng, Cheng, Xianshuo, Zhu, Ying, Yuan, Wenli, Dong, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920511/
https://www.ncbi.nlm.nih.gov/pubmed/33658858
http://dx.doi.org/10.2147/CMAR.S281925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920511/
https://www.ncbi.nlm.nih.gov/pubmed/33658858
http://dx.doi.org/10.2147/CMAR.S281925

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