Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV

Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part...

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Detalles Bibliográficos
Autores principales: Gil, Eliza, Sweeney, Nicola, Barrett, Veronica, Morris-Jones, Stephen, Miller, Robert F., Johnston, Victoria J., Brown, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920675/
https://www.ncbi.nlm.nih.gov/pubmed/33622490
http://dx.doi.org/10.3201/eid2703.202359
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author Gil, Eliza
Sweeney, Nicola
Barrett, Veronica
Morris-Jones, Stephen
Miller, Robert F.
Johnston, Victoria J.
Brown, Michael
author_facet Gil, Eliza
Sweeney, Nicola
Barrett, Veronica
Morris-Jones, Stephen
Miller, Robert F.
Johnston, Victoria J.
Brown, Michael
author_sort Gil, Eliza
collection PubMed
description Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part of combination therapy for 2 patients with disseminated nontuberculous mycobacteria co-infected with HIV.
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spelling pubmed-79206752021-03-04 Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV Gil, Eliza Sweeney, Nicola Barrett, Veronica Morris-Jones, Stephen Miller, Robert F. Johnston, Victoria J. Brown, Michael Emerg Infect Dis Dispatch Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance and adverse effects of prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part of combination therapy for 2 patients with disseminated nontuberculous mycobacteria co-infected with HIV. Centers for Disease Control and Prevention 2021-03 /pmc/articles/PMC7920675/ /pubmed/33622490 http://dx.doi.org/10.3201/eid2703.202359 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Gil, Eliza
Sweeney, Nicola
Barrett, Veronica
Morris-Jones, Stephen
Miller, Robert F.
Johnston, Victoria J.
Brown, Michael
Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
title Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
title_full Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
title_fullStr Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
title_full_unstemmed Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
title_short Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV
title_sort bedaquiline as treatment for disseminated nontuberculous mycobacteria infection in 2 patients co-infected with hiv
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920675/
https://www.ncbi.nlm.nih.gov/pubmed/33622490
http://dx.doi.org/10.3201/eid2703.202359
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