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Lin28 Inhibits the Differentiation from Mouse Embryonic Stem Cells to Glial Lineage Cells through Upregulation of Yap1

The RNA-binding protein Lin28 regulates neurogliogenesis in mammals, independently of the let-7 microRNA. However, the detailed regulatory mechanism remains obscured. Here, we established Lin28a or Lin28b overexpression mouse embryonic stem cells (ESCs) and found that these cells expressed similar l...

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Detalles Bibliográficos
Autores principales:	Luo, Juan, Zou, Hailin, Deng, Liang, Sun, Xiang, Yuan, Ping, Li, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920735/ https://www.ncbi.nlm.nih.gov/pubmed/33688355 http://dx.doi.org/10.1155/2021/6674283

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