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Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency

BACKGROUND: One strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy (ART) is to activate latent HIV infection with a latency reversing agent (LRA). Surrogate markers that accurately measure virus production following an LRA...

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Detalles Bibliográficos
Autores principales: Zerbato, Jennifer M., Khoury, Georges, Zhao, Wei, Gartner, Matthew J., Pascoe, Rachel D., Rhodes, Ajantha, Dantanarayana, Ashanti, Gooey, Megan, Anderson, Jenny, Bacchetti, Peter, Deeks, Steven G., McMahon, James, Roche, Michael, Rasmussen, Thomas A., Purcell, Damian FJ, Lewin, Sharon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920823/
https://www.ncbi.nlm.nih.gov/pubmed/33647768
http://dx.doi.org/10.1016/j.ebiom.2021.103241

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