Cargando…
Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency
BACKGROUND: One strategy being pursued to clear latently infected cells that persist in people living with HIV (PLWH) on antiretroviral therapy (ART) is to activate latent HIV infection with a latency reversing agent (LRA). Surrogate markers that accurately measure virus production following an LRA...
Autores principales: | Zerbato, Jennifer M., Khoury, Georges, Zhao, Wei, Gartner, Matthew J., Pascoe, Rachel D., Rhodes, Ajantha, Dantanarayana, Ashanti, Gooey, Megan, Anderson, Jenny, Bacchetti, Peter, Deeks, Steven G., McMahon, James, Roche, Michael, Rasmussen, Thomas A., Purcell, Damian FJ, Lewin, Sharon R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920823/ https://www.ncbi.nlm.nih.gov/pubmed/33647768 http://dx.doi.org/10.1016/j.ebiom.2021.103241 |
Ejemplares similares
-
Diverse effects of interferon alpha on the establishment and reversal of HIV latency
por: Van der Sluis, Renée M., et al.
Publicado: (2020) -
Memory CD4(+) T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency
por: Rasmussen, Thomas A., et al.
Publicado: (2022) -
HIV DNA persists in hepatocytes in people with HIV-hepatitis B co-infection on antiretroviral therapy
por: Zerbato, Jennifer M., et al.
Publicado: (2022) -
Persistence of envelopes in different CD4(+) T-cell subsets in antiretroviral therapy-suppressed people with HIV
por: Gartner, Matthew J., et al.
Publicado: (2023) -
GITR activation ex vivo impairs CD8 T cell function in people with HIV on antiretroviral therapy
por: Gubser, Céline, et al.
Publicado: (2023)