DNA stability: a central design consideration for DNA data storage systems

Data storage in DNA is a rapidly evolving technology that could be a transformative solution for the rising energy, materials, and space needs of modern information storage. Given that the information medium is DNA itself, its stability under different storage and processing conditions will fundamen...

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Detalles Bibliográficos
Autores principales: Matange, Karishma, Tuck, James M., Keung, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921107/
https://www.ncbi.nlm.nih.gov/pubmed/33649304
http://dx.doi.org/10.1038/s41467-021-21587-5
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author Matange, Karishma
Tuck, James M.
Keung, Albert J.
author_facet Matange, Karishma
Tuck, James M.
Keung, Albert J.
author_sort Matange, Karishma
collection PubMed
description Data storage in DNA is a rapidly evolving technology that could be a transformative solution for the rising energy, materials, and space needs of modern information storage. Given that the information medium is DNA itself, its stability under different storage and processing conditions will fundamentally impact and constrain design considerations and data system capabilities. Here we analyze the storage conditions, molecular mechanisms, and stabilization strategies influencing DNA stability and pose specific design configurations and scenarios for future systems that best leverage the considerable advantages of DNA storage.
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spelling pubmed-79211072021-03-12 DNA stability: a central design consideration for DNA data storage systems Matange, Karishma Tuck, James M. Keung, Albert J. Nat Commun Review Article Data storage in DNA is a rapidly evolving technology that could be a transformative solution for the rising energy, materials, and space needs of modern information storage. Given that the information medium is DNA itself, its stability under different storage and processing conditions will fundamentally impact and constrain design considerations and data system capabilities. Here we analyze the storage conditions, molecular mechanisms, and stabilization strategies influencing DNA stability and pose specific design configurations and scenarios for future systems that best leverage the considerable advantages of DNA storage. Nature Publishing Group UK 2021-03-01 /pmc/articles/PMC7921107/ /pubmed/33649304 http://dx.doi.org/10.1038/s41467-021-21587-5 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review Article
Matange, Karishma
Tuck, James M.
Keung, Albert J.
DNA stability: a central design consideration for DNA data storage systems
title DNA stability: a central design consideration for DNA data storage systems
title_full DNA stability: a central design consideration for DNA data storage systems
title_fullStr DNA stability: a central design consideration for DNA data storage systems
title_full_unstemmed DNA stability: a central design consideration for DNA data storage systems
title_short DNA stability: a central design consideration for DNA data storage systems
title_sort dna stability: a central design consideration for dna data storage systems
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921107/
https://www.ncbi.nlm.nih.gov/pubmed/33649304
http://dx.doi.org/10.1038/s41467-021-21587-5
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AT keungalbertj dnastabilityacentraldesignconsiderationfordnadatastoragesystems

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