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Degradable polymeric vehicles for postoperative pain management
Effective control of pain management has the potential to significantly decrease the need for prescription opioids following a surgical procedure. While extended release products for pain management are available commercially, the implementation of a device that safely and reliably provides extended...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921139/ https://www.ncbi.nlm.nih.gov/pubmed/33649338 http://dx.doi.org/10.1038/s41467-021-21438-3 |
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author | Brigham, Natasha C. Ji, Ru-Rong Becker, Matthew L. |
author_facet | Brigham, Natasha C. Ji, Ru-Rong Becker, Matthew L. |
author_sort | Brigham, Natasha C. |
collection | PubMed |
description | Effective control of pain management has the potential to significantly decrease the need for prescription opioids following a surgical procedure. While extended release products for pain management are available commercially, the implementation of a device that safely and reliably provides extended analgesia and is sufficiently flexible to facilitate a diverse array of release profiles would serve to advance patient comfort, quality of care and compliance following surgical procedures. Herein, we review current polymeric systems that could be utilized in new, controlled post-operative pain management devices and highlight where opportunities for improvement exist. |
format | Online Article Text |
id | pubmed-7921139 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-79211392021-03-12 Degradable polymeric vehicles for postoperative pain management Brigham, Natasha C. Ji, Ru-Rong Becker, Matthew L. Nat Commun Perspective Effective control of pain management has the potential to significantly decrease the need for prescription opioids following a surgical procedure. While extended release products for pain management are available commercially, the implementation of a device that safely and reliably provides extended analgesia and is sufficiently flexible to facilitate a diverse array of release profiles would serve to advance patient comfort, quality of care and compliance following surgical procedures. Herein, we review current polymeric systems that could be utilized in new, controlled post-operative pain management devices and highlight where opportunities for improvement exist. Nature Publishing Group UK 2021-03-01 /pmc/articles/PMC7921139/ /pubmed/33649338 http://dx.doi.org/10.1038/s41467-021-21438-3 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Perspective Brigham, Natasha C. Ji, Ru-Rong Becker, Matthew L. Degradable polymeric vehicles for postoperative pain management |
title | Degradable polymeric vehicles for postoperative pain management |
title_full | Degradable polymeric vehicles for postoperative pain management |
title_fullStr | Degradable polymeric vehicles for postoperative pain management |
title_full_unstemmed | Degradable polymeric vehicles for postoperative pain management |
title_short | Degradable polymeric vehicles for postoperative pain management |
title_sort | degradable polymeric vehicles for postoperative pain management |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921139/ https://www.ncbi.nlm.nih.gov/pubmed/33649338 http://dx.doi.org/10.1038/s41467-021-21438-3 |
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