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The effect of electroconvulsive therapy on neuroinflammation, behavior and amyloid plaques in the 5xFAD mouse model of Alzheimer’s disease

Microglial cells are affected in Alzheimer’s disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory loss, depression is common in patients with AD. Electroconvulsive therapy (ECT) is an anti-depressive treatment that may stimulate microglia, induce neuroinflammation and alter th...

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Detalles Bibliográficos
Autores principales: Svensson, Martina, Olsson, Gustaf, Yang, Yiyi, Bachiller, Sara, Ekemohn, Maria, Ekstrand, Joakim, Deierborg, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921388/
https://www.ncbi.nlm.nih.gov/pubmed/33649346
http://dx.doi.org/10.1038/s41598-021-83998-0