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Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation

In this article, a novel susceptible–infected–recovered epidemic model with nonmonotonic incidence and treatment rates is proposed and analyzed mathematically. The Monod–Haldane functional response is considered for nonmonotonic behavior of both incidence rate and treatment rate. The model analysis...

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Autores principales: Kumar, Abhishek, Nilam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921616/
https://www.ncbi.nlm.nih.gov/pubmed/33680706
http://dx.doi.org/10.1007/s40304-020-00217-4
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author Kumar, Abhishek
Nilam
author_facet Kumar, Abhishek
Nilam
author_sort Kumar, Abhishek
collection PubMed
description In this article, a novel susceptible–infected–recovered epidemic model with nonmonotonic incidence and treatment rates is proposed and analyzed mathematically. The Monod–Haldane functional response is considered for nonmonotonic behavior of both incidence rate and treatment rate. The model analysis shows that the model has two equilibria which are named as disease-free equilibrium (DFE) and endemic equilibrium (EE). The stability analysis has been performed for the local and global behavior of the DFE and EE. With the help of the basic reproduction number [Formula: see text] , we investigate that DFE is locally asymptotically stable when [Formula: see text] and unstable when [Formula: see text] . The local stability of DFE at [Formula: see text] has been analyzed, and it is obtained that DFE exhibits a forward transcritical bifurcation. Further, we identify conditions for the existence of EE and show the local stability of EE under certain conditions. Moreover, the global stability behavior of DFE and EE has been investigated. Lastly, numerical simulations have been done in the support of our theoretical findings.
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spelling pubmed-79216162021-03-02 Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation Kumar, Abhishek Nilam Commun Math Stat Article In this article, a novel susceptible–infected–recovered epidemic model with nonmonotonic incidence and treatment rates is proposed and analyzed mathematically. The Monod–Haldane functional response is considered for nonmonotonic behavior of both incidence rate and treatment rate. The model analysis shows that the model has two equilibria which are named as disease-free equilibrium (DFE) and endemic equilibrium (EE). The stability analysis has been performed for the local and global behavior of the DFE and EE. With the help of the basic reproduction number [Formula: see text] , we investigate that DFE is locally asymptotically stable when [Formula: see text] and unstable when [Formula: see text] . The local stability of DFE at [Formula: see text] has been analyzed, and it is obtained that DFE exhibits a forward transcritical bifurcation. Further, we identify conditions for the existence of EE and show the local stability of EE under certain conditions. Moreover, the global stability behavior of DFE and EE has been investigated. Lastly, numerical simulations have been done in the support of our theoretical findings. Springer Berlin Heidelberg 2021-03-02 2022 /pmc/articles/PMC7921616/ /pubmed/33680706 http://dx.doi.org/10.1007/s40304-020-00217-4 Text en © School of Mathematical Sciences, University of Science and Technology of China and Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Kumar, Abhishek
Nilam
Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation
title Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation
title_full Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation
title_fullStr Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation
title_full_unstemmed Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation
title_short Effects of Nonmonotonic Functional Responses on a Disease Transmission Model: Modeling and Simulation
title_sort effects of nonmonotonic functional responses on a disease transmission model: modeling and simulation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921616/
https://www.ncbi.nlm.nih.gov/pubmed/33680706
http://dx.doi.org/10.1007/s40304-020-00217-4
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