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Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease

To characterize rod- and cone-pathway function in the 5xFAD mouse model of Alzheimer’s disease (AD) using the full-field electroretinogram (ERG). Dark-adapted (DA; rod-pathway) and light-adapted (LA; cone-pathway) ERGs were recorded from three-month-old 5xFAD and wild type (WT) mice. ERGs were elici...

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Detalles Bibliográficos
Autores principales: McAnany, J. Jason, Matei, Nathanael, Chen, Yi-Fan, Liu, Karen, Park, Jason C., Shahidi, Mahnaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921657/
https://www.ncbi.nlm.nih.gov/pubmed/33649406
http://dx.doi.org/10.1038/s41598-021-84318-2