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Cysteine metabolic circuitries: druggable targets in cancer
To enable survival in adverse conditions, cancer cells undergo global metabolic adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling on three different levels: first, in its free form, in redox control, as a component of the antioxidant glutathione or its involve...
Autores principales: | Bonifácio, Vasco D. B., Pereira, Sofia A., Serpa, Jacinta, Vicente, João B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921671/ https://www.ncbi.nlm.nih.gov/pubmed/33223534 http://dx.doi.org/10.1038/s41416-020-01156-1 |
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