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Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids
The mechanical properties of the extracellular matrix strongly influence tumor progression and invasion. Yes-associated protein (YAP) has been shown to be a key regulator of this process translating mechanical cues from the extracellular matrix into intracellular signals. Despite its apparent role i...
Autores principales: | Illes, Bernhard, Fuchs, Adrian, Gegenfurtner, Florian, Ploetz, Evelyn, Zahler, Stefan, Vollmar, Angelika M., Engelke, Hanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921841/ https://www.ncbi.nlm.nih.gov/pubmed/33718837 http://dx.doi.org/10.1016/j.isci.2021.102185 |
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