TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions

Estrogen receptor-α (ER) drives tumor development in ER-positive (ER+) breast cancer. The transcription factor GATA3 has been closely linked to ER function, but its precise role in this setting remains unclear. Quantitative proteomics was used to assess changes to the ER complex in response to GATA3...

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Detalles Bibliográficos
Autores principales: Broome, Rebecca, Chernukhin, Igor, Jamieson, Stacey, Kishore, Kamal, Papachristou, Evangelia K., Mao, Shi-Qing, Tejedo, Carmen Gonzalez, Mahtey, Areeb, Theodorou, Vasiliki, Groen, Arnoud J., D’Santos, Clive, Balasubramanian, Shankar, Farcas, Anca Madalina, Siersbæk, Rasmus, Carroll, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921846/
https://www.ncbi.nlm.nih.gov/pubmed/33626359
http://dx.doi.org/10.1016/j.celrep.2021.108776

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