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Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine
Traditional Chinese medicine (TCM) was the primary source of medical treatment for the people inhabiting East Asia for thousands of years. These ancient practices have incorporated a wide variety of materia medica including plants, animals and minerals. As modern sciences, including natural products...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Society of Applied Pharmacology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921859/ https://www.ncbi.nlm.nih.gov/pubmed/33632986 http://dx.doi.org/10.4062/biomolther.2020.229 |
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author | Deyrup, Stephen T. Stagnitti, Natalie C. Perpetua, Mackenzie J. Wong-Deyrup, Siu Wah |
author_facet | Deyrup, Stephen T. Stagnitti, Natalie C. Perpetua, Mackenzie J. Wong-Deyrup, Siu Wah |
author_sort | Deyrup, Stephen T. |
collection | PubMed |
description | Traditional Chinese medicine (TCM) was the primary source of medical treatment for the people inhabiting East Asia for thousands of years. These ancient practices have incorporated a wide variety of materia medica including plants, animals and minerals. As modern sciences, including natural products chemistry, emerged, there became increasing efforts to explore the chemistry of this materia medica to find molecules responsible for their traditional use. Insects, including beetles have played an important role in TCM. In our survey of texts and review articles on TCM materia medica, we found 48 species of beetles from 34 genera in 14 different families that are used in TCM. This review covers the chemistry known from the beetles used in TCM, or in cases where a species used in these practices has not been chemically studied, we discuss the chemistry of closely related beetles. We also found several documented uses of beetles in Traditional Korean Medicine (TKM), and included them where appropriate. There are 129 chemical constituents of beetles discussed. |
format | Online Article Text |
id | pubmed-7921859 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Society of Applied Pharmacology |
record_format | MEDLINE/PubMed |
spelling | pubmed-79218592021-03-02 Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine Deyrup, Stephen T. Stagnitti, Natalie C. Perpetua, Mackenzie J. Wong-Deyrup, Siu Wah Biomol Ther (Seoul) Review Traditional Chinese medicine (TCM) was the primary source of medical treatment for the people inhabiting East Asia for thousands of years. These ancient practices have incorporated a wide variety of materia medica including plants, animals and minerals. As modern sciences, including natural products chemistry, emerged, there became increasing efforts to explore the chemistry of this materia medica to find molecules responsible for their traditional use. Insects, including beetles have played an important role in TCM. In our survey of texts and review articles on TCM materia medica, we found 48 species of beetles from 34 genera in 14 different families that are used in TCM. This review covers the chemistry known from the beetles used in TCM, or in cases where a species used in these practices has not been chemically studied, we discuss the chemistry of closely related beetles. We also found several documented uses of beetles in Traditional Korean Medicine (TKM), and included them where appropriate. There are 129 chemical constituents of beetles discussed. The Korean Society of Applied Pharmacology 2021-03-01 2021-03-01 /pmc/articles/PMC7921859/ /pubmed/33632986 http://dx.doi.org/10.4062/biomolther.2020.229 Text en Copyright © 2021, The Korean Society of Applied Pharmacology This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Deyrup, Stephen T. Stagnitti, Natalie C. Perpetua, Mackenzie J. Wong-Deyrup, Siu Wah Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine |
title | Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine |
title_full | Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine |
title_fullStr | Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine |
title_full_unstemmed | Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine |
title_short | Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine |
title_sort | drug discovery insights from medicinal beetles in traditional chinese medicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921859/ https://www.ncbi.nlm.nih.gov/pubmed/33632986 http://dx.doi.org/10.4062/biomolther.2020.229 |
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