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Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis

OBJECTIVE: The intestinal epithelial barrier (IEB) restricts the passage of microbes and potentially harmful substances from the lumen through the paracellular space, and rupture of its integrity is associated with a variety of gastrointestinal disorders and extra-digestive diseases. Increased IEB p...

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Detalles Bibliográficos
Autores principales: Olivier, Séverine, Pochard, Camille, Diounou, Hanna, Castillo, Vanessa, Divoux, Jordane, Alcantara, Joshua, Leclerc, Jocelyne, Guilmeau, Sandra, Huet, Camille, Charifi, Wafa, Varin, Thibault V., Daniel, Noëmie, Foretz, Marc, Neunlist, Michel, Salomon, Benoit L., Ghosh, Pradipta, Marette, André, Rolli-Derkinderen, Malvyne, Viollet, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921883/
https://www.ncbi.nlm.nih.gov/pubmed/33548500
http://dx.doi.org/10.1016/j.molmet.2021.101183